| VCU Rams vs Virginia Tech Hokies | Apr 21 05:00 PM | -105 | -119 | -111 | -120 | 6.7% | 5 |
| Wright St Raiders vs Cincinnati Bearcats | Apr 21 07:00 PM | -209 | +170 | -235 | +154 | 6.5% | 6 |
| Texas A&M Aggies vs UTSA Roadrunners | Apr 21 08:00 PM | -260 | +200 | -300 | +188 | 6.9% | 7 |
| Miami (OH) RedHawks vs Michigan Wolverines | Apr 21 08:30 PM | -124 | -102 | -125 | -106 | 6.6% | 5 |
| Appalachian St Mountaineers vs East Tennessee St Buccaneers | Apr 21 10:00 PM | -105 | -119 | -111 | -120 | 6.7% | 5 |
| Bethune-Cookman Wildcats vs UCF Knights | Apr 21 10:00 PM | +214 | -260 | +190 | -303 | 7% | 5 |
| Charlotte 49ers vs Campbell Fighting Camels | Apr 21 10:00 PM | +100 | -130 | +100 | -133 | 6.6% | 5 |
| UNC Wilmington Seahawks vs Coastal Carolina Chanticleers | Apr 21 10:00 PM | -190 | +154 | -210 | +145 | 6.7% | 6 |
| Liberty Flames vs Duke Blue Devils | Apr 21 10:00 PM | +190 | -236 | +172 | -260 | 6.5% | 6 |
| North Florida Ospreys vs Florida St Seminoles | Apr 21 10:00 PM | -364 | +275 | -400 | +250 | 6.8% | 7 |
| North Carolina Tar Heels vs High Point Panthers | Apr 21 10:00 PM | +320 | -445 | +300 | -500 | 6.8% | 7 |
| Purdue Boilermakers vs Indiana St Sycamores | Apr 21 10:00 PM | +190 | -225 | +165 | -250 | 6.4% | 5 |
| Rutgers Scarlet Knights vs St. John's Red Storm | Apr 21 10:00 PM | -200 | +160 | -210 | +149 | 6.1% | 3 |
| Florida Gators vs Jacksonville St Gamecocks | Apr 21 10:30 PM | -500 | +340 | -500 | +340 | 6.1% | 1 |
| West Virginia Mountaineers vs Pittsburgh Panthers | Apr 21 10:30 PM | +154 | -189 | +141 | -210 | 6.7% | 7 |
| Alabama Crimson Tide vs UAB Blazers | Apr 21 11:00 PM | -300 | +250 | -350 | +220 | 6.8% | 7 |
| Arkansas Razorbacks vs Missouri St Bears | Apr 21 11:00 PM | -160 | +130 | -175 | +124 | 6.8% | 7 |
| Arkansas-Little Rock Trojans vs UT Rio Grande Valley Vaqueros | Apr 21 11:00 PM | -115 | -115 | -115 | -115 | 7% | 3 |
| Clemson Tigers vs South Carolina Upstate Spartans | Apr 21 11:00 PM | -284 | +220 | -300 | +203 | 6.4% | 5 |
| Georgia Bulldogs vs Georgia Tech Yellow Jackets | Apr 21 11:00 PM | +115 | -139 | +105 | -150 | 6.9% | 7 |
| Troy Trojans vs Jacksonville St Gamecocks | Apr 21 11:00 PM | -161 | +130 | -170 | +121 | 6.1% | 5 |
| Kansas Jayhawks vs Nebraska Cornhuskers | Apr 21 11:00 PM | +105 | -129 | -103 | -140 | 6.9% | 7 |
| Louisville Cardinals vs Kentucky Wildcats | Apr 21 11:00 PM | -115 | -115 | -115 | -115 | 7% | 5 |
| Northwestern St Demons vs UL Monroe Warhawks | Apr 21 11:00 PM | -145 | +115 | -150 | +110 | 6.2% | 4 |
| Oklahoma St Cowboys vs Wichita St Shockers | Apr 21 11:00 PM | -180 | +145 | -192 | +140 | 6.3% | 5 |
| Southern Miss Golden Eagles vs Tulane Green Wave | Apr 21 11:00 PM | -253 | +200 | -275 | +183 | 6.5% | 6 |
| Nevada Wolf Pack vs Saint Mary's Gaels | Apr 21 11:05 PM | -110 | -119 | -111 | -120 | 6.9% | 3 |
| Rice Owls vs Houston Cougars | Apr 21 11:30 PM | -115 | -114 | -116 | -115 | 7% | 4 |
| Illinois Fighting Illini vs Illinois St Redbirds | Apr 21 11:30 PM | -275 | +225 | -310 | +198 | 6.4% | 5 |
| CSU Fullerton Titans vs USC Trojans | Apr 22 01:00 AM | +162 | -200 | +149 | -225 | 6.4% | 6 |
| CSU Northridge Matadors vs San Diego St Aztecs | Apr 22 01:00 AM | -120 | -105 | -120 | -110 | 6.6% | 4 |
| UCLA Bruins vs Hawai'i Rainbow Warriors | Apr 22 01:00 AM | +550 | -901 | +500 | -1200 | 6.6% | 7 |
| Washington Huskies vs Portland Pilots | Apr 22 01:00 AM | -142 | +120 | -160 | +107 | 6.4% | 5 |